a) What is the reaction mechanism for the synthesis of the substituted aromatic molecule: 4-Nitroacetanilid?
b) explain each step in the reaction mechanism.
a) What is the reaction mechanism for the synthesis of the substituted aromatic molecule: 4-Nitroacetanilid? b) explain...
4. Is this molecule aromatic? Explain why or why not. For each molecule below, predict whether the molecule would be expected to show aromatic character or not. Explain your answer in each case. 5. (f 6. Is this molecule aromatic, antiaromatic, or nonaromatic? Explain.
perform an aromatic substitution reaction with this
molecule. Please provide the recipe, the mechanism (arrow pushing),
and the product.
why would the chosen position be affected?
" NH2 NH zorom
draw a line reaction for the best workable synthesis of
substituted benzophenone
2. In your inventory, you have the chemicals chlorobenzene, tert- butylbenzene, 4-chlorobenzoyl chloride, and 4-tert-butyl)benzoyl chloride. You also have all common Lewis acids. Draw a line reaction for the best workable synthesis of the substituted benzophenone shown below. Explain your process in about two sentences of writing.
Friedel - Craft Acylation Synthesis of 4-Methoxiacetophenone Background Information 1.- What is an electrophilic aromatic substitution? 2.- Give three examples of activating groups. Explain why they activate the ring for substitution. 3.- Give three examples of deactivating groups. Explain why they deactivate the ring for substitution. 4.- Describe the difference between a Friedel-Craft alkylation and Acylation. Synthesis of 4-Methoxiacetophenone For this Friedel-Craft acylation we will react Anisole with Acetic Anhydride. Write the mechanism and the structure of the final product....
Please explain:)
3. Aromatic or no? Label each of the following compounds as aromatic, non-aromatic, or anti- aromatic, and explain each answer briefly. 4. Design a multi-step synthesis for the following transformation. For EAS reactions, you may make a mixture of ortho and para products and then simply state "separate" to give you the desired isomer. CH3 CH3 OH CH3 toluene NO2 NO2
Please help... Need a detail Mechanism of this reaction.
Thanks...
Electrophilic aromatic substitution describes the reaction where a hydrogen from a benzene ring is replaced by an electrophile. Halogenation, nitration, sulfonation, alkylation and acylation are all possible using this type of reaction. The electrophile attacks the pi electrons of the aromatic ring, yielding a benzenonium ion. The substituted aromatic product is obtained when a proton is lost, restoring the aromatic system. If there is a substituent on the aromatic ring...
8. 11 pt 4-chlorobenzaldehyde and 4-bromoacetophenone are both solid starting materials for the synthesis of substituted chalcone. When both of these compounds are ground with solid sodium hydroxide, the entire reaction mixture turns liquid. Explain why the solid reactants turn liquid when intimately mixing them. (Hint: What are the final products of the reaction?)
8. 1 pt] 4-chlorobenzaldehyde and 4-bromoacetophenone are both solid starting materials for the synthesis of substituted chalcone. When both of these compounds are ground with solid sodium hydroxide, the entire reaction mixture turns liquid. Explain why the solid reactants turn liquid when intimately mixing them. (Hint: What are the final products of the reaction?)
3. Devise a multi-step synthesis of the target molecule from the given starting material. Show all necessary reagents and conditions for each step and the product of each step. (7) OH BONUS: Please provide the arrow pushing mechanism of this reaction. Be sure to show a charges and stereochemistry where needed. To receive full credit, what is the name of this reaction? (4) NaOE HOE Br
4. Provide a plausible mechanism for the reaction shown. (6 pts) 7 NaNH. Hycor ND 5. Each transformation shown below requires at least two steps. Provide the reagents/conditions for each transformation. (20 pts) Reagents Reagents A! Reagents D-7 Reagents Reagents 6. Predict the products from the Birch reductions shown below. (3 pts) Nz, NHU CH OH Bonus: (6 pts) Provide a synthesis for the target molecule using benzene. CO2H CO2H TM 1. Draw Frost circle diagrams for each compound shown....