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udy: Gastroesophageal Reflux Disease Question5 The health care provider prescribes omeprazole for Mr. Liston and instructs him to return for a follow-up visit in two weeks if his symptoms do not improve. What is the mechanism of action of omeprazole and the rationale for returning only if symptoms persist? Question If medications and lifestyle modifications are not effective at eliminating the symptoms of GERD, what is another option?
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5.Mechanism of action of omeprazole - oomeprazole is a proton pump inhibitor which blocks the gastricH,K-ATPase(hydrogen/pottasium adenosine triphosphatase enzyme) reducing the production of acid in the wall of the stomach. Its action is pronounced and long term.

The patient is asked to come for follow if symptoms persist because alternative diagnosis can be made excluding GERD and also to find out weekly acidic reflux in patient and also the side effects of medicine.

6. If medicine and lifestyle changes does not work for GERD then surgeries can be done as per doctor's order..

​Fundoplication -wrapping the top of stomach to tighten up the muscles to prevent reflux.

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