Explain mechanistically how DMF catalyzes the formation of the acid chloride (in the synthesis of N,N-Diethyl-m-toluamide)
Explain mechanistically how DMF catalyzes the formation of the acid chloride (in the synthesis of N,N-Diethyl-m-toluamide)
explain mechanistically how DMF catalyzed the formation of the acid chloride
The top half of the image depicts the reaction of the synthesis of N,N-diethyl-m-toluamide (DEET). The bottom half of the image attached shows the table of chemicals used in the reaction. How would I calculate the theoretical yield and furthermore, the percent yield? This experiment had a lot of chemicals used, and I don't know where to start. SOC (CH, CH2), NH -(CH₃ CH₂)₂NH₂ cr CN(CH₂ CH₂), - HD, -50, mame molecular formula Quantity density maar gwel thinyl chloride sou,...
(9) 8. Show how you would accomplish the following multistep synthesis: Synthesize the insect repellent N,N-diethyl-n-toluamide from m-toluic acid. Use compounds with no more than 5 carbons as your other reagents. NC CH 3 2 from
Propose a stepwise mechanism for the synthesis of N,N-diethyl-m-toluamide (DEET). please show all steps! thanks (CH,CHy), WH -CH,CH) NHCr N(CH, CH,) SOCI -HCI CAM3 -5 CAM
CH20% O C CH 20% SOCl2, pyr (CH3CH2)2NH CH3 CH3 N,N-Diethyl-m-toluamide (DEET) 3. a. Why is the amine added in a solution of sodium hydroxide? b. Both the amine and hydroxide ion are good nucleophiles. Why doesn't the hydroxide attack the acid chloride in this reaction? 4. In the absence of pyridine, a prominent peak at 1780 cm appears in the IR spectrum of the product. Explain.
Why does the amine react with the acid chloride in preference to the water (or hydroxide) in the two phase mixture? What is the role of the hydroxide solution? (in the preparation of N,N-Diethyl-m-toluamide)
Please analyze the IR and NMR spectra. The product is N,N-diethyl-m-toluamide. The product is obtained by the following reactions Please label all major peaks. Solvent is Et2O. Extracted with NaOH and then HCl and then H2O. Dried and then evaporated. To further purify, hexane was used in column chromatography to elute the product. Then evaporated. CH3 CH3 SOCI2 + SO2 O=0 ОН CH3 CH3 -- + excess (CH3CH2)2NH + (CH3CH2)2NH2* crt ether CI 'N-CH2CH3 CH,CHE 1000 11 100 100 100...
Starting with a fatty acid located in the cytosol of the cell, explain “mechanistically” how a pantothenic acid deficiency may result in reduced acetyl CoA production from beta oxidation of palmitic acid.
A student mixes 3.00 mL of m-toluoyl chloride (154.59 g/mol, 1.173 g/mL) with excess diethylamine to produce 2.38 mL of N,N-diethyl-m-toluamide (191.27 g/mol, 0.998 g/mL). What is the percent yield of this student's experiment?
11) Show how to synthesize 2-Methylhexanoic acid using the Malonic Ester Synthesis. Start with Diethyl propanedioate (C7H1204)