Devise a synthesis of each substituted cyclopropane. Use acetylene (HC≡CH) as a starting material in part...

Question

Question

Devise a synthesis of each substituted cyclopropane. Use acetylene (HC≡CH) as a starting material in part...

Devise a synthesis of each substituted cyclopropane. Use acetylene (HC≡CH) as a starting material in part (a), and cyclohexanone as a starting material in part (b). You may use any other organic compounds and any needed reagents.

a.
b.

science chemistry

Add a comment Improve this question Transcribed image text

Answer 1

Answer #1

a.

Sodium amide abstracts a proton from acetylene to form acetylide anion which then attacks the carbon atom bearing bromine atom to give substituted alkyne.

Acetylene proton is abstracted by base sodium amide to give acetylide anion which then attacks the carbon atom bearing bromine atom to give substituted alkyne.

Alkyne is reduced to cis-alkene by treating the alkyne with in the presence of Lindlar’s catalyst.

Alkene reacts with in the presence of to give the desired product.

b.

Cyclohexanone reacts with bromine in the presence of acetic acid to give 2-bromocyclohexanone.2-bromocyclohexanone reacts with strong base to give unsaturated carbonyl compound.

Dimethyl lithium cuprate reacts with cyclohex-2-enone to give 3-methyl-cyclohexanone.

The compound, 3-methyl-cyclohexanone reacts with to give 1-methyl-3-methylenecyclohexane.1-methyl-3-methylenecyclohexane reacts with chloroform in the presence of strong base to give 1,1-dichloro-5-methylspiro[2.5]octane.

The compound, 1,1-dichloro-5-methylspiro[2.5]octane reacts with dimethyl lithium cuprate to give desired product.

Add a comment

Answer 2

Similar Homework Help Questions

Devise a synthesis of each substituted cyclopropane. Use acetylene (HC≡CH) as a starting material in part...

Devise a synthesis of each substituted cyclopropane. Use acetylene (HC≡CH) as a starting material in part (a), and cyclohexanone as a starting material in part (b). You may use any other organic compounds and any needed reagents.a. b.
Devise a synthesis of the following compound from the indicated starting material, organic compounds containing one or...

Devise a synthesis of the following compound from the indicated starting material, organic compounds containing one or two carbons, and any other required reagents. Be sure to answer all parts. Devise a synthesis of the following compound from the indicated starting material, organic compounds containing one or two carbons, and any other required reagents. Be sure to answer all parts. (+ enantiomer) CECH edit structure ... CH,CI edil structure. edit structure
Devise a synthesis of CH_3CH_2C CCH_2CH_2OH using CH_3CH_2CH CH_2 as the starting material. You may use...

Devise a synthesis of CH_3CH_2C CCH_2CH_2OH using CH_3CH_2CH CH_2 as the starting material. You may use any other organic compounds or inorganic reagentd. Be sure to answer all parts.

(14) V. Starting from benzene and any other reagents you need, propose an efficient synthesis of th following compound. (10) VI. Devise a synthesis that will accomplish the following transformati...

(14) V. Starting from benzene and any other reagents you need, propose an efficient synthesis of th following compound. (10) VI. Devise a synthesis that will accomplish the following transformation in good yield. Use the given compounds as the only organic source of carbon atoms. You may use any common organic solvents as well as any needed inorganic reagents (14) V. Starting from benzene and any other reagents you need, propose an efficient synthesis of th following compound. (10) VI....
3) Devise a synthesis of the following compound using the given compounds (you may use each...

3) Devise a synthesis of the following compound using the given compounds (you may use each one more than once if needed). You may also use any needed inorganic or organic reagents but all of the carbons in the target molecule must come from the given starting materials. Hint: this synthesis will require you to use ozonolysis and a reaction that starts with the letter DI
Devise a synthesis of the following compound using the given compounds

Devise a synthesis of the following compound using the given compounds (you may use each one more than once if needed). You may also use any needed inorganic or organic reagents but all of the carbons in the target molecule must come from the given starting materials.

Synthesis question... I just need help with the structures. Thanks Devise a synthesis of CH3CH2CECCH2CH2OH using...

Synthesis question... I just need help with the structures. Thanks Devise a synthesis of CH3CH2CECCH2CH2OH using CH3CH2CH- CH2 as the starting material. You may use any other organic compounds or inorganic reagents. Be sure to answer all parts. OH Step 1 LICI 2 equiv CI2 SOCI Intermediate 1: edit structure
Devise a synthesis of the following compounds from the given starting material and any other required...

Devise a synthesis of the following compounds from the given starting material and any other required reagents several steps OH yan several steps Br several steps ore
11. Write out a step wise synthesis of the following compounds starting from acetylene. You may...

11. Write out a step wise synthesis of the following compounds starting from acetylene. You may use any other reagents necessary. a. b. HO

6. (18 points total) Synthesis: Devise a synthesis of the following compound from the given starting...

6. (18 points total) Synthesis: Devise a synthesis of the following compound from the given starting materials. You may use any other organic or inorganic reagents you deem necessary but you must use the given starting materials as your only source of carbon in the final compound OH several steps OH MeOH HO

Devise a synthesis of each substituted cyclopropane. Use acetylene (HC≡CH) as a starting material in part...

Homework Answers

Add Answer to:
Devise a synthesis of each substituted cyclopropane. Use acetylene (HC≡CH) as a starting material in part...

Post as a guest

Earn Coins