Question

1.) Show how to carry out the following transformation in the highest yield possible. Select the appropriate reagents and draw the correct organic product at each step

2. and 3.) In each reaction box, place the best reagent and conditions from the list below.



In each reaction box, place the best reagent and c

In each reaction box, place the best reagent and c

In each reaction box, place the best reagent and c

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Answer #1
Concepts and Reason

This problem is based on the concept of fridal craft alkylation and acylation reaction of benzene.

Benzene is an electron rich species which undergoes electrophilic substitution reactions.

Fridal craft alkylation and acylation also comes in the category of electrophilic substitution reaction of benzene. In this reaction, alkyl group and acyl group are electrophilic substituents.

Fundamentals

In fridal craft alkylation and acylation, compounds like AlCl3{\rm{AlC}}{{\rm{l}}_3} and FeCl3{\rm{FeC}}{{\rm{l}}_3} work as catalyst in anhydrous form in order to form an electrophile substituted product.

Part 1.1

The reaction is given below:

HỌC CH
C-Cl / FeCl2

Part 1.2

The reaction is given below:

нс-Сн
Нc-Сн,
CI, FeCI,
CI
1. Zn(Hg)/HCI
O=C
-
0-с
2. NaOH

Part 2

The reaction conversion is given below:

CI , AICI
Bry/FeBrz
ВГ
H3C-CH2-CI, AICI,

Part 3

The reactions involved in the conversion are as follows:

och
oh ou
Zn(Hg)/HCI
on

Ans: Part 1.1

The structure of the product is as follows:

ง=0
มว-

Part 1.2

The structure of compound which is formed in between is as follows:

нс-Сн
ord

Part 2

The sequence of reaction involved in the chemical conversion is as follows:

1. / CI , AICI,
2. Bry/FeBrz
3. H2C-CH2-CI, AICI

Part 3

The sequence of reaction involved in the chemical conversion is as follows:

1. cry
, AICI,
Oooo
2. Zn(Hg)/HCI

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