• . Design a synthesis to achieve the desired regiochemistry of a multisubstituted benzene ring Interconvert...
Objectives-Section 3 Design a synthesis to achieve the desired regiochemistry of a multisubstituted benzene ring Interconvert between ortho/para- and meta-directing groups to carry out synthe ses Incorporate blocking groups to design a synthes is involving electrophilic aromatic substitution. Propose a synthesis of the following conversion: 3. a) NO COOH b)
Aromatic Synthesis Reactions Starting with benzene, propose syntheses to carry out each of the following conversions. Assume ortho and para isomers can be separated.
Please help... Need a detail Mechanism of this reaction. Thanks... Electrophilic aromatic substitution describes the reaction where a hydrogen from a benzene ring is replaced by an electrophile. Halogenation, nitration, sulfonation, alkylation and acylation are all possible using this type of reaction. The electrophile attacks the pi electrons of the aromatic ring, yielding a benzenonium ion. The substituted aromatic product is obtained when a proton is lost, restoring the aromatic system. If there is a substituent on the aromatic ring...
Predict the effect the substituent attached to the benzene ring below would have on electrophilic aromatic substitution reactions? CH, CH3 a) meta director, deactivator b) ortho/para director, activator c) meta director, activator d) ortho/para director, deactivator
1. Complete the following exercises: A. Indicate whether each substituted benzene ring will produce predominantly ortho/para or meta products) after electrophilic aromatic substitution: B. Identify the molecule that can undergo nucleophilic aromatic substitution by addition/elimination:
Question 3. [time 4 + 8 = 12 minutes) (a) i. Both the regioselectivity and the rate of an electrophilic aromatic substitution are affected by the substituents already attached to the benzene ring. Some groups promote substitution at the ortho or para positions, while other groups increase substitution at the meta position. Explain the terms "resonance effect" and "inductive effect" of substituents (use words and schemes). ii. Explain, using words and schemes, how in electrophilic aromatic substitutions existing substituents direct...
437 Predict whether the following substituents on the benzene ring are likely to be ha para directing or meta directing and whether they are like to be ring activating or ring deactivating deact vabang a) - NH(CH 4.38 For each of the monosabstituted benenes shown below, (1) Indicate whether the substituent is ortho, para directing or meta directing (2) Draw the structure of the main monosubstitution product for each of the reactions indicated orth. OCH3 + HCl -OCHE (fecutulys ortho...
10. (12 points) Cua CHaCHa Les eb Predict whether the following substituents on the benzene ring are likely to be ortho/para directing or meta directing and whether they are likely to be ring activating or ring deactivating ..n(CH3)2 CEN ОСН з -NO C-OCH 11. (6 points) Starting with benzene as the only aromatic starting material, devise a
Synthesis of disubstituted benzenes involves two steps, each introducing one of the functional groups For the synthesis of p-chlorosulfonic acid, select the reagent for each step and draw the structure of the monosubstituted intermediate compound. Put the intermediate substituent in the same place that it is oberved in the product (i.e. either the top or the bottom of the benzene ring). Intermediate Step 1 Step 2 O C2, peroxide O Ch. FeCl3 O SOs, H2S04 O Cl2. peroxide O Cl2....
1. please check what is wrong. Thank you! Determine the product formed when each compound is treated with Br2 and FeBr3. Drag the atom labels to their appropriate positions. CN Atom labels H H Br Br2 A. FeBr Br H OH OH Br Br. Br2 FeBr3 H H Br Br H Br2 FeBr H1 H Reset T Rank the compounds in each group in order of decreasing reactivity in electrophilic aromatic substitution. CI Decreasing reactivity Rank the compounds in each...