Question

Indicate the stereochemical configuration for the tetrahedral centers shown below.

Indicate the stereochemical configuration for the tetrahedral centers shown below. R S not a configuration center R S not a configuration center

Answer 1

In stereo compounds, the stereocenters are labeled as R or S To labelled the compounds as R and S, substituents must be prioritized according to certain rules A substituent with a higher atomic number takes priority over a substituent with a lower atomic number. Due to lowest atomic number hydrogen is the lowest possible priority substituent. the lowest priority substituent should always point away from the viewer. Imagine an arrow that drawn from the highest priority atom to the next highest priority atom to lowest priority atom. If the arrow points in a counter clockwise direction the configuration at stereocenter will be considered S. Here, S stands for "Sinister" that means left

If the arrow points in clockwise direction the configuration at stereocenter will be considered R. Here, R stands for "Rectus" that means right. The stereochemical configuration for the tetrahedral centers are shwon below. NH2 (R)-butan-2-amine (R)-3-bromobut-1-ene Both the tetrahedral centers shows R-configuration