Provide an efticient synthesis tor each of the tollowing transtormations: OCH3 OH CN 1 N 2....
5. Design a short synthesis to accomplish the following transformations کر دی۔ OH H OCH3 CN OH OET Br NH2 ti - OCH3 H 7 — OH INCIN (H3C) N OCH3 Br oil
9. Provide a stepwise synthesis to carry out the following conversions CN Br Br (a) (b) 2 но,S OH
S. Provide the reagents necessary for these 2 step synthesis problems OH .N&.ON > Br OH OH Br 7 OH h. OH H OH H 1. Os k.
OCH3 OH from One route to the synthesis of HO and CH,CH2MgBr is to 1) protect the ketone as an acetal, 2) reduce the ester to an alcohol, 3) hydrolyze the acetal back to the ketone, 4) protect the alcohol as a TMS ether, 5) react the ketone with the Grignard reagent followed by acidic workup to give the desired product. A second route to the desired product would start with the selective reduction of only the ketone to an...
2. Propose and efficient synthesis for each of the following transformations. [20] CN Br OH IIOH + enantiomer
1) Propose a synthesis of the following CN AH NC Hot 2) Propose a synthesis. Но, OH
4. Provide the products of each reaction (3pts. 2pts) 1. H30 OCH3 2. NaOCH; CHOH2 OCH 3. Ht, A 4. NaCN 1. LDA 2 Pho 3. H+, A 4 EtMg Br
Practice Set-l1 SET-IV Br Br CH3 HO2C .CN 1. 4. Br Cl C OH 2. 5 OH 3. ON 6. 9ON NO2 NH2 1. N2* N(CH3)2 _OSHN OH 3. 02N N2 4, N2 HSO4 2. NH2 02N OH NH2 e.l pH< 6 2 03S S03 ESO3 Practice Set-l1 SET-IV Br Br CH3 HO2C .CN 1. 4. Br Cl C OH 2. 5 OH 3. ON 6. 9ON NO2 NH2 1. N2* N(CH3)2 _OSHN OH 3. 02N N2 4, N2 HSO4...
Propose an efficient synthesis for each of the following transformations: O OH. - H20 1) [H*), HO 2) NaNH2 3) Eti 1) [H"), HO 2) Eti O H. - H2O 4) H30* OH-H20 1) [H"). HO 2) NaNH2 3) Eti 4) H30 O H. - H20 1) [H*). HO 2) NaNH2 3) H30 ОН 1) [н']), но 2) LiAIH, он, - H,0 он, - H,0 1) [н'], но 2) Н, 3) НО* 1) [н'], но 2) H2 он, -но он,...
What is the best reagent to complete this synthesis? 1) ???? OH 2) NaCN CN 1) PBr3 2) CISiMe3 3) SoCl2 4) MSCI