Suggest a synthesis of 1, using as starting materials the Her o CO,Et es -CHO 4....
| -COEU CHO 4 = 4. a) Lily aldehyde (1) is an ingredient used in perfumery. Suggest a synthesis of 1, using as starting materials, the ester 2 and 1-propanol. You may use any other applicable inorganic and/or organic reagents, but LiAlH, NaOH (aq). PCC, H2, DIBAL, and Pd/C are the most likely choices (depending on your synthetic route). No reaction mechanism(s) is required. Lily aldehyde О Мете b) Using 2-methyl-1,3-cyclopentanedione, acetaldehyde and acetone as your only sources of carbon,...
A co₂Et 4. A Chem 241 student was given an experiment to synthesize compoun OH acetoacetate. The student prepared 1 mole equivalent of methylmagnesium lo which was then slowly added to a solution of ethyl acetoacetate in ether. Every 1 went well, Indeed, even without the annlication of heat the reaction mixture Dubbie orking carefully, with supervision and advice from the lab instructor, the student worked- up the reaction and isolate - LII Caction and isolated an excellent vield of...
Suggest a synthesis for compound 1 using as starting materials/reactants benzaldehyde, bromoethane, and Ph3P+Ch3Br- and the following reagents/conditions Mg; PCC; HzO2, NaOH; H3O+; BuLI; and BH3, THF (c) Suggest a synthesis for compound 1 using as starting materials/reactants benzaldehye, bromoethane, and Ph3P CH3 Br- and the following reagents/conditions - Mg; PCC; H2O2, NAOH; H30* BuLi; and BH3, THF. Use of the starting materials/reactants and reagents/conditions is strongly recommended in order to solve. Start by counting the HO DBH3,1HF total number...
PROBLEM o Using retro-synthesis or synthetic design propose a route for the following conversion. dando o Draw all the forward reactions to complete the work (synthesis); o Starting with 1-pentyne synthesize 1,1-dichloro-cis-2,3- dipropylcyclopane using any alkyl iodide and any other necessary inorganic or organic reagents. I-penye
Give a reasonable synthesis for each of the following compounds from the indicated starting materials. You may use any other organic or inorganic reagents you wish unless otherwise indicated. The desired product for each reaction you propose must be the one of the predominant products. Give the reactants, conditions (where appropriate) and products of each synthetic step. If equal mixtures are anticipated (i.e. ortho / para products) then indicate where separations are needed. NO MECHANISMS! [6 points 2. Give a...
Provide a multistep synthesis for the desired product using the indicated starting materials. You may use any additional organic or inorganic reagents. Do not draw any curved-arrow mechanisms. The best answ will require nine or fewer steps. OH 었 OET NH2 Starting Materials NH3 OH Desired Product
9.RETROSYNTHETIC ANALYSIS Give a reasonable synthesis for the following compound from the indicated starting materials. You may use any other organic reagents or inorganic reagents you wish. The desired product for each reaction must be the MAJOR PRODUCT. Give the reactants, conditions (where appropriate), and products of each synthetic step but NO MECHANISMS. [4 points) OH Use to make HO
Suggest suitable starting materials and reagents for the synthesis of 2-allyl-4-phenylcyclohexanone using enolate alkylation reactions. Select one: a. i) 4-phenylcyclohexanone, LDA ii) allyl bromide b. i) 4-benzylcyclohexanone, LDA ii) allyl chloride c. i) allyl bromide, LDA ii) 4-phenylcyclohexanone d. i) 3-phenylcyclopentanone, LDA ii) allyl bromide e. i) 4-phenylcyclohexanone, triethylamine ii) allyl bromide
4. Devise a synthesis of X from the given starting materials. You may use any organic or inorganic reagents. Account for the stereochemistry observed in X.
Suggest suitable starting materials and reagents for the synthesis of 3-cyclopentyl-4-methyl-2-pentanone using enolate alkylation reactions. Select one: a. i) 3-methyl-2-pentanone, LDA ii) bromocyclopentane b. i) 4-ethyl-2-pentanone, LDA ii) bromocyclopentane c. i) 4-methyl-2-pentanone, NaH ii) bromocyclohexane d. i) 4-methyl-2-pentanone, LDA ii) bromocyclopentane e. i) 3-methyl-2-butanone, pyridine ii) bromocyclopentane