Suggest suitable starting materials and reagents for the
synthesis of 3-cyclopentyl-4-methyl-2-pentanone using enolate
alkylation reactions.
Select one:
a. i) 3-methyl-2-pentanone, LDA ii) bromocyclopentane
b. i) 4-ethyl-2-pentanone, LDA ii) bromocyclopentane
c. i) 4-methyl-2-pentanone, NaH ii) bromocyclohexane
d. i) 4-methyl-2-pentanone, LDA ii) bromocyclopentane
e. i) 3-methyl-2-butanone, pyridine ii) bromocyclopentane
Suggest suitable starting materials and reagents for the synthesis of 3-cyclopentyl-4-methyl-2-pentanone using enolate a...
Suggest suitable starting materials and reagents for the synthesis of 2-allyl-4-phenylcyclohexanone using enolate alkylation reactions. Select one: a. i) 4-phenylcyclohexanone, LDA ii) allyl bromide b. i) 4-benzylcyclohexanone, LDA ii) allyl chloride c. i) allyl bromide, LDA ii) 4-phenylcyclohexanone d. i) 3-phenylcyclopentanone, LDA ii) allyl bromide e. i) 4-phenylcyclohexanone, triethylamine ii) allyl bromide
12. In a synthesis of isopropyl pyridine, the 3-methyl-2- presence of sodium ethoxide to give a dicarbonyl compo NaOCH.CH opropyl pyridine, the 3 with ethyl formate in the 0 ethyl formate 3-methyl-2-butanone a) In the first step of the mechanism, sodiu alpha position to form an enolate. Complete the as necessary (4 points) step of the mechanism, sodium ethoxide deprotonates 3-methyl-2-buthone at the O form an enolate, Complete this reaction with curly arrows drawing in H atoms b) Why is...
Suggest a synthesis of 1, using as starting materials the Her o CO,Et es -CHO 4. a) Lily aldehyde (1) is an ingredient used in perfumery. Suggest a synthesis of 1, using as starting materials, the ester 2 and 1-propanol. You may use any other applicable inorganic and/or organic reagents, but LiAIH, NaOH (aq). PCC, H2, DIBAL, and Pd/C are the most likely choices (depending on your synthetic route). No reaction mechanism(s) is required. Lily aldehyde b) Using 2-methyl-1,3-cyclopentanedione, acetaldehyde...
6.24 With methyl, ethyl, or cyclopentyl halides as your organic starting materials and using any needed solvents or inorganic reagents, outline syntheses of each of the following. More than one step may be necessary and you need not repeat steps carried out in earlier parts of this problem (a) CH3 (e) CH3SH (i) CH30CH3 (b) (f) (j) SH OMe (c) CH3OH (g) CH3CN (d) (h) CN ОН
Devise a synthesis of (Z)-4-methyl-2-pentene using one of the starting materials and any of the reagents below using the fewest steps possible. If you need fewer than the 3 steps allowed, enter "none" for reagents in the remaining unused steps. Starting materials HC=CH HC=C-CH, HC=C-CH,CH, сн. HC=C-CH2CH2CH2CH2HC=C-C-CH, von CH, HC=C-¢-CH, . CHO Reagents a NaNH, NH(l) diodoethane g 1-bromo-3-methylbutane į Hy / Lindlar catalyst - Na0H: H0 e 1-bromopropane ht-butyl bromide k H / NH (1) ciodomethane f 2-bromopropane i...
choose a starting material (4-methyl-2-pentanone, 2-methyl-3-pentanone, 2,3-dimethylbutanal) and a reagent from A-F to synthesize 2,2-dimethoxy-4-methylpentane. Choose a starting material and a reagent (A-F) to synthesize the given product. When [Select ] is treated with (Select ] it will produce 2,2-dimethoxy-4- methylpentane. REAGENTS C. A. Jones' reagent, Croz in CH3MgBr (in CH3OH ether) (excess) followed by acid-catalyst, H30(+) workup heat (-H20) H₂O(+) NaBH4 in CH3OH (CH2)5NH (piperidine) N2H4 KOH & acid-catalyst, strong heat heat (-H20)
Answer both parts (i) and (ii) (i) Suggest suitable reagents for the following transformations. H3C 2. он +HPO NH2 CH3 5 marks (ii) For the reactions given above in part (i) label the main functional groups of the starting materials and the products given. 5 marks] Answer both parts (i) and (ii) (i) Suggest suitable reagents for the following transformations. H3C 2. он +HPO NH2 CH3 5 marks (ii) For the reactions given above in part (i) label the main...
le chatelier experimen Thursday). 1. What starting material and reagents are needed for the following multi-step synthesis (HINT: aldol reactions work best when the starting material can only form one enolate)? 5 он о D. NaOH, H2O, Heat F. HO E. NaOH, H2O G. LDA Starting Material: Reagents: 2. LDA is a strong, sterically hindered base and will form the enolate. Sodium hydride is a weak base and will form the _ - enolate. Kinetic enolates are the stable and...
"uctions down Question 1 Pe Which reagents would favor the formation of 3-methyl 2-butanone from 2-butanone? 1. Nah, 25°C 2.CHgBr O H20 / CH2BE O 1. LDA -78°C 2.CH3Br O Both A and B all the reagents would give that product Question 2 2.5 pts
Suggest a synthesis for compound 1 using as starting materials/reactants benzaldehyde, bromoethane, and Ph3P+Ch3Br- and the following reagents/conditions Mg; PCC; HzO2, NaOH; H3O+; BuLI; and BH3, THF (c) Suggest a synthesis for compound 1 using as starting materials/reactants benzaldehye, bromoethane, and Ph3P CH3 Br- and the following reagents/conditions - Mg; PCC; H2O2, NAOH; H30* BuLi; and BH3, THF. Use of the starting materials/reactants and reagents/conditions is strongly recommended in order to solve. Start by counting the HO DBH3,1HF total number...