.
1. Nausea is the first experienced ,then salivary secretion is increased and breathing become deep ,rapid and irregular.
2. Retching may occur which consist of.
• incoordinated spasmodic contraction of respiratory muscles , and
• descent of diaphragm when expiratory muscles contract.
3. Glottis closes and remains shut till expulsion of vomited material is effected.this increases intra-pulmonary pressure causing compression of esophagus.This also prevents aspiration of vomitus into the trachea.
4. Pyloric part contracts firmly and at the same time body of stomach relaxes so that gastric contents are forced into it; anti-peristalsis may take place in stomach.
5. Flaccid stomach is compressed by the raised intra-abdominal pressure resulting from descent of diaphragm and contraction of abdominal wall.
6. The cardiac sphincter and esophagus relaxes and gastric contents are,therefore,driven into the dilated esophagus .
7. Oesophagus contracts by:
• increased intra-pulmonary pressure.
• active contraction throughout its length,or
• a wave of anti- peristalsis may pass over it.
8. Soft palate is raised and shuts off the nasal cavity from the throat.
9. Towards the end of act of vomiting.
• diaphragm relaxes ,i.e it ascends ; and
• expiratory muscles and abdominal wall contracts.
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