Question

For each reaction between a ketone and an amine, draw the curved arrow(s) to show the...

For each reaction between a ketone and an amine, d

For each reaction between a ketone and an amine, draw the curved arrow(s) to show the first step of the mechanism, then draw the final organic product. (If you accidentally changed the structures given in the problem, click on the red over/under arrows to remove any changes you have made.)

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Concepts and reason

This problem is based on the concept of curved arrow representation of reaction of carbonyl compounds with amines.

Carbonyl compounds (aldehydes and ketones) are highly reactive towards nucleophile due to their highly electrophilic character. They undergo many nucleophilic addition reactions in order to give various organic compounds. Amines are highly nucleophilic in nature due the presence of lone pair of electrons on nitrogen.

Fundamentals

Amines are highly nucleophilic in nature due the presence of lone pair of electrons on nitrogen and attacks on the electrophiles like carbonyl compounds due to its electron density.

[Part 1]

The reaction mechanism is given below:

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The curved arrow representation of chemical reaction along with the product is given below:

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[Part 2]

The reaction mechanism is given below:

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The curved arrow representation of chemical reaction along with the product is given below:

Ans: Part 1

The curved-arrow representation of chemical reaction along with the final product is shown below:

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Part 2

The curved-arrow representation of chemical reaction along with the final product is shown below:

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