wone br Provide the products of the following reaction scheme. 5' x 9 45 1)O 2)...
19. (Spts total) Match the reagents with the product if the starting material is: Reagent Product Br Br, HO I) RCO H 2) H,O Br он КМпО. NaOH, cold HBr, ROOR A X Он ) Hg(OAc)p.H;O X2) NaBH Br 1) BHy THF 2) H2O2, NaOH "Вг F. он Н.Pt "Вг G. он ) O 2) DMS "ОН Он HBr X OH Br2
For each of the following reaction sequences provide the structure of the final product. If there is more than one step, provide the structure(s) of any intermediate products. 1) Oso/H,02 4. H₃C CH₃ Will the product be a meso compound? 1) BH, THE 2) NaOH, HCO3 H₃C 1) H0/H Hac 1) Hg(OAC), in H,0 2) NaBH 1) NaNH, 2) (CH),CH,CH,Br 3) H,SO/H,0/ Hg(OAC), HCECH 1) NaNH, 2) (CH),CH,CH,Br 3) (Sia),BH 4) NaOH! Hoa Page 2 of 5
Give the missing reagent(s). Matching H2SO., H30 Cl2 1) Br, H;O 2) NaH KMnO Cold, Dilute,Basic HCI 1) BH THE 2) H2O2, OH 1) Hg(OAc), H:0 2) NaBH, OH 1) Os 2) (CH3)2S H20, H SO. mCPBA 1) mCPBA 2) H30 Na. 1) OsO. 2) NaHSO; Liquid NH; 1) mCPBA 2) H30, OH Lindlar's Catalyst
9. Predict the major products for the following reactions. Show the stereochemistry of the products) when applicable.. (a) HIB ROOR (1) Hg(OAc), HO (2) NaBH (1) BH, THE (2) 1,0, OH Br. H.O Pt (1) Oso (2) NaHSOHO (1) 03 (2) DMS (1) CHCO,H (2) H0+ Page 2 of 2
4. Design a synthetic plan for the following conversions; Meaning you need to write each reaction product for each step presented on the arrow. First one is solved as an example. 1. U. neat OH 2. Oso / NaHSO, / H,0 OH (meso 1.H2SOheat V 2. Oso NaHSO, /HO cys hydroxilation (meso) 1. HBr, ROOR 2.HCSc. (rac) 1. Br hy 2. KOH, ETOH VOM EIO 3. mCPBA/H,O* (rac) 1. NBS, by 2. H. Ni 3. KtBuo, ETOH 4. Hg(OAC),/CH,OH /...
11. Predict the product for the following reaction 1) Hg(OAC), 2) NaBH, 12. Predict the product for the following reaction. 1. Br /H,O 2. NaOH Br ОН OH
Provide the major product(s) for the following reactions: Show Stereochemistry when necessary (10 points total) Br HBr CH2CI Br2 HBr Но ROOR CH,OH Н,о н* Н,о° 1) Hg(O,CCF3)2 CH,OH 1) BН, THF 2) H,О, NaOH, Нао 2) NaBH, NaOH 1) Hg(OAc) Н0, THF/ Hа Pd/C 2) NaBH, NaOH
Complete all of the following reactions by drawing structures of the major products for each. Where appropriate, clearly indicate stereochemistry of the product. Н, РО, 2 Br 3. (1)OsO (2)NaHSO) Cl2/H2O 5. ()Bн, (2)H,O2OH(a 6- (1O (2)Zn, H 1. CHClyNaOH 8. (1)Hg 2+ (2)NaBH 9. KMnO. HO 10. 41
draw the missing structures for the letters Scheme 1 Br S NaOH CI + A B + С H2N NH2 Scheme 2 1. MCPBA Na2Cr2O7 D E 2. H20, H30+ H30+ Scheme 3 1. LIAIH4 PBr3 F G Н 2. H30+ ether Scheme 4 1. H20, Hg(OAc)2 DMP H I 2. NaBH4 CH2Cl2 Scheme 5 OH tosyl chloride Na J K pyridine ОН
Ivan Martinen -4. What is the best choice of reagent to perform the following reaction? A. BH, 2)+H,0 B. HgSo. 2)+ NaBH C. H,O, H.SO. D. Oso, 2)+NaHSO OH ... 5. What is the best choice of reagent to perform the following reaction? A. BH, 2)+H,0 B. HgSo. 2)+ NaBH, C. HO, H,SO. D. Oso. )+NaHSO, он