In a similar experiment, unlabeled 4-butanolide was allowed to stand in an acidic solution...
In a similar experiment, unlabeled 4-butanolide was allowed to stand in an acidic solution in which the water had been labeled with 18O. When the lactone was extracted from the solution after four days, it was found to contain 18O. Which oxygen of the lactone do you think became isotopically labeled?
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