Protein kinase specificity via consensus target sequences and intrasteric control
Consult Table 15.2 and
a. Suggest a consensus amino acid sequence within phosphorylase kinase that makes it a target of protein kinase A (the cAMP-dependent protein kinase).
b. Suggest an effective amino acid sequence for a regulatory domain pseudosubstrate sequence that would exert intrasteric control on phosphorylase kinase by blocking its active site.
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