Problem

Reduction Potentials in the Electron Transport ChainMATHEMATICAL Using the information in...

Reduction Potentials in the Electron Transport Chain

MATHEMATICAL Using the information in Table, calculate ΔG°'for the following reaction:

Table The Energetics of Electron Transport Reactions

Reaction	ΔG°' kJ (mol NADH)−1	kcal (mol NADH)−1
NADH+H+ E—FMN → NAD+ E—FMNH2	−38.6	−9.2
E—FMNH2+CoQ → E—FMN + CoQH2	−42.5	−10.2
CoQH2 + 2 Cyt b[Fe(III)] → CoQ + 2H+ + 2 Cyt b[Fe(II)]	+11.6	+2.8
2 Cyt b[Fe(II)] + 2 Cyt c1 [Fe(III)] → 2 Cyt c1[Fe(II)]+ 2 Cyt b[Fe(III)]	−34.7	−8.3
2 Cyt c1[Fe(II)] + 2 Cyt c[Fe(III)] → 2 Cyt c[Fe(II)] + 2 Cyt c1[Fe(III)]	−5.8	−1.4
2 Cyt c[Fe(II)] + 2 Cyt (aa3)[Fe(III)] + 2 Cyt (aa3)[Fe(II)] + 2 Cyt c[Fe(III)]	-7.7	−1.8
2 Cyt (aa3)[Fe(II)]+ O2 + 2H+ → 2 Cyt (aa3)[Fe(III)]+H2O	−102.3	−24.5
Overall reaction: NADH+H+ + O2 → NAD+ + H2O	−220	−52.6