The difference between water-soluble and fat-soluble vitamins is their molecular structure...

The difference between water-soluble and fat-soluble vitamins is their molecular structures. Water-soluble vitamins tend to have multiple polar groups that can interact with water to form hydrogen bonds, whereas fat-soluble vitamins tend to be nonpolar molecules consisting predominately of hydrocarbon chains. This is an example of what is meant by the expression “like dissolves like.” Predict whether vitamin C and vitamin E will be water soluble or fat soluble.