Problem

The drug cidofovir is approved by the Federal Drug Administration (FDA) for the treatment...

The drug cidofovir is approved by the Federal Drug Administration (FDA) for the treatment of certain viral infections of the eye in patients with compromised immune systems. It is distributed in vials containing 375 mg of the drug dissolved in 5 mL of water. The manufacturer specifies that the drug should be kept at room temperature (68°F−77°F). The vial contents are first diluted with saline and then administered intravenously with a recommended dosage of 5 mg cidofovir per kilogram of body weight, (a) Convert cidofovir’s recommended storage-temperature range to the Celsius scale, (b) If the fluid in a single vial of cidofovir has a volume of 5.00 mL and a mass of 5.89 g, what is the density of the fluid, in g/mL. to the appropriate number of significant figures? (c) Convert the density in part (b) to g/L and to kg/m3, (d) What mass of cidofovir should be administered to a 185-lb man?

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