Problem

Avidin is a protein that binds extremely tightly to biotin. Therefore, it is a potent inhi...

Avidin is a protein that binds extremely tightly to biotin. Therefore, it is a potent inhibitor of biotin-requiring enzyme reactions. Consider glucose biosynthesis from each of the following substrates and predict which of these pathways would be inhibited by avidin.

(a) Lactate


 (b) Oxaloacetate


 (c) Malate


 (d) Fructose-6-phosphate


 (e) Phosphoenolpyruvate

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Solutions For Problems in Chapter 12