Problem

Folic acid is synthesized in bacteria as dihydrofolate, in a pathway starting from guanosi...

Folic acid is synthesized in bacteria as dihydrofolate, in a pathway starting from guanosine triphosphate, In this pathway, C-8 is lost as formate. From the structural similarities between guanine and pterin, predict which carbon and nitrogen atoms of GTP are the precursors to N-l, C-2, C-4, N-5, C-7, N-8, and C-9 of dihydrofolate.

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Solutions For Problems in Chapter 20