Problem

Solutions For An Introduction to Medicinal Chemistry Chapter 6 Problem 3Q

Step-by-Step Solution

Solution 1

Nitrogen bases have two primary divisions; one division represents pyrimidine another division represents purine bases. The adenine (A) base is categorized under purine and thymine (T) is considered among the pyrimidine group.

Purine is a derivative of pyrimidine. It consists of a pyrimidine ring and a five membered imidazole ring (having nitrogen at 7 and 9 positions), which are fused together at 5 and 4 positions. There are two purine compounds, namely adenine (A) and guanine (G).

It is very clear to identify CN (carbon-nitrogen) bonded through double bonds in the aromatic ring. These double bonds are resonating continuously. The cyanide molecules are shown clearly in the diagram below.

Figure: The cyanide molecules

4 molecules of HCN (hydrogen cyanide) condense to form 2, 3-diaminomaleonitrile, which then isomerizes to form a ring cyclic structure. Another molecule of HCN condenses with this ring to form adenine nucleotide.

Add your Solution
Textbook Solutions and Answers Search
Solutions For Problems in Chapter 6