Problem

Procaine (its hydrochloride salt is marketed as Novocaine) was one of the first local an...

Procaine (its hydrochloride salt is marketed as Novocaine) was one of the first local anesthetics developed for infiltration and regional anesthesia. It is synthesized by the following Fischer esterification:

(a) Draw the structural formula of Procaine.

(b) Which of the two nitrogen atoms in Procaine is the stronger base? (Chapter 8)

(d) Would you predict Procaine or Novocaine to be more soluble in blood?

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Solutions For Problems in Chapter 18

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