9. It is observed that as temperature is increased, most protein molecules go from their defined, folded state into a random-coil, denatured state which exposes more hydrophobic surface area than is exposed in the folded state.
(a) Given what you have learned so far about ΔH and ΔS, explain why this is reasonable. [Hint: Consider Problem 7.]
(b) Sometimes, however, proteins denature as temperature is decreased. How might this be explained? [Hint: Consider Problem 8.]
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