In evaluating jaundiced patients, clinicians often determine whether the bilirubin that accumulates in the blood is primarily free bilirubin or the diglucuromide, Which form would accumulate primarily in chronic liver disease? In bile duct obstruction by a gallstone? In bcmolytic are mia, such as that associated with glucose-6-phosphate dehydromgenase deficiency (see Chapter 13)? Breifly explain your answere.
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