Recall that we discussed two different types of selection in this chapter: selection of different virus strains within one host and selection of those virus strains that are able to transmit themselves from host to host. Now consider the hypothesis, traditionally championed by biomedical researchers, that disease-causing agents naturally evolve into more benign forms as the immune systems of their hosts evolve more efficient responses to them. Is the evidence we have reviewed on the evolution of HIV within and among hosts consistent with this hypothesis? Why or why not?
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