Problem

Healthy Teeth II Exercise 10.25 describes a dental experiment conducted to investiga...

Healthy Teeth II Exercise 10.25 describes a dental experiment conducted to investigate the effectiveness of an oral rinse used to inhibit the growth of plaque on teeth. Subjects were divided into two groups: One group used a rinse with an antiplaque ingredient, and the control group used a rinse containing inactive ingredients. Suppose that the plaque growth on each person’s teeth was measured after using the rinse after 4 hours and then again after 8 hours. If you wish to estimate the difference in plaque growth from 4 to 8 hours, should you use a confidence interval based on a paired or an unpaired analysis? Explain.

Reference:

Healthy Teeth Jan Lindhe conducted a study on the effect of an oral antiplaque rinse on plaque buildup on teeth.6 Fourteen people whose teeth were thoroughly cleaned and polished were randomly assigned to two groups of seven subjects each. Both groups were assigned to use oral rinses (no brushing) for a 2-week period. Group 1 used a rinse that contained an antiplaque agent. Group 2, the control group, received a similar rinse except that, unknown to the subjects, the rinse contained no antiplaque agent. A plaque index x, a measure of plaque buildup, was recorded at 14 days with means and standard deviations for the two groups shown in the table.

a. State the null and alternative hypotheses that should be used to test the effectiveness of the antiplaque oral rinse.

b. Do the data provide sufficient evidence to indicate that the oral antiplaque rinse is effective? Test using α = .05.

c. Find the approximate p-value for the test.

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