Problem

Diphenadione inhibits the clotting of blood; that is, it is an anticoagulant. It is used t...

Diphenadione inhibits the clotting of blood; that is, it is an anticoagulant. It is used to control vampire bat populations in South America by a “Trojan horse” strategy. A few bats are trapped, smeared with diphenadione, and then released back into their normal environment. Other bats, in the course of grooming these diphenadione-coated bats, ingest the anticoagulant and bleed to death, either internally or through accidental bites and scratches.

Suggest a synthesis of diphenadione from 1,1-diphenylacetone and dimethyl 1,2- benzenedicarboxylate.

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