Rough endoplasmic reticulum is responsible for protein synthesis and membrane production.
Hence, the option A is incorrect.
Lysosomes are responsible for intracellular digestion. Lysosomes can hydrolyze proteins, fats, sugars, and nucleic acids.
Hence, the option C is incorrect.
Packing, processing and shipping organelle that is called Golgi Apparatus. It is responsible to transport materials from the Endoplasmic Reticulum throughout the cell.
Hence, the option D is incorrect.
Endoplasmic Reticulum lacks ribosomes and is referred to as a Smooth endoplasmic reticulum, and it is responsible for the function as Detoxification and metabolism of multiple molecules.
Hence, the option is correct.