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Solutions For An Introduction to Medicinal Chemistry Chapter 11 Problem 9Q

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Solution 1

The half-life of a drug is defined as the period of time after which only half of the original drug concentration remains in the body. Hence, it can be said that when the half-life of the drug is passed, its concentration reduces by half.

The relationship between the half life and concentration of a drug can be defined as an exponential one. Suppose that a drug has a half life of 4 hours. That means that after every four hours, the concentration of the drug is halved.

Hence, in a time period of 24 hours, the concentration of the drug would be halved 6 times. Hence, the final concentration of the drug can be determined as below:

As a result, the final concentration of the drug is.

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Solutions For Problems in Chapter 11