Understanding the role of phosphocreatine
ATP stores in muscle are augmented or supplemented by stores of phosphocreatine. During periods of contraction, phosphocreatine is hydrolyzed to drive the synthesis of needed ATP in the creatine kinase reaction:
Phosphocreatine + ADPcreatine + ATP
Muscle cells contain two different isozymes of creatine kinase, one in the mitochondria and one in the sarcoplasm. Explain.
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