Problem

Consider three facts: (i) Loss of heterozygosity may be especially detrimental at MHC loci...

Consider three facts: (i) Loss of heterozygosity may be especially detrimental at MHC loci, because allelic variability at these loci enhances disease resistance; (ii) Microsatellite loci show that the gray wolves on Isle Royale, Michigan, are highly inbred (Wayne et al. 1991); (iii) This wolf population crashed during an outbreak of canine parvovirus during the 1980s. How might these facts be linked? What other hypotheses could explain the data? How could you test your ideas?

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Solutions For Problems in Chapter 7