Problem

Use the PDR®, to find another product name for each drug in the Representative Drugs table...

Use the PDR®, to find another product name for each drug in the Representative Drugs table on pages 370–371 of this text.

Representative Drugs for the Reproductive System
Category, Namea, and Route	Uses and Diseases		Actions		Usual Doseb and Special Instructions	Side Effects and Adverse Reactions
Hormones
Conjugated estrogens (Premarin) Oral, cream, IM, IV	Abnormal uterine bleeding; menopausal symptoms; breast and inoperable prostate cancer		Replaces estrogen		Postmenopause: 0.3–1.25 mg/day for 3 weeks, then 1 week off; repeat cycle Cancer: 1.25 mg tid daily as ordered by physician	Nausea, breakthrough bleeding, fluid retention
Oxytocin (Pitocin, Syntocinon) IV, IM	Induction or stimulation of labor, incomplete abortion, control of postpartum bleeding		Stimulates uterine and mammary glands		10–40 units in 1000 mL D5W or normal saline	Hypertension, arrhythmias, seizures, coma, effects on fetus, bradycardia, tachycardia, irregular heartbeat, anoxia, asphyxia
Medroxyprogesterone acetate (Provera) Oral, IM	Dysfunctional uterine bleeding, amenorrhea, endometrial cancer, contraception		Suppresses ovulation		5–10 mg po for 5–10 days; administer with food if gastric upset occurs	Breast tenderness, weight changes, fluid retention, thrombophlebitis, pulmonary embolism, dizziness, migraines, breakthrough bleeding
Methyltestosterone (Metandren) Oral, buccal	Male: Hypogonadism Female: Cancer of the breast, postpartum breast engorgement		Stimulates spermatogenesis, development of male sex characteristics, sexual maturity		Male: 10–50 mg/day po Female: 80 mg/day po for 3–5 days or 40 mg/ day buccal for breast engorgement; 200 mg/day po or 100 mg/day buccal for cancer; do not swallow or chew buccal medications; do not eat, drink, or smoke until buccal medication has dissolved	Male: Jaundice, edema Female: Amenorrhea, virilization, hair growth, acne, change in libido (sex drive)
Antibacterials
Miconazole (Monistat 7) Suppository, cream	Local vaginal infections caused by Candida fungus		Is a fungicidal agent		1 suppository or applicator full of cream once daily at bedtime for 7 days; protect underclothing	Vaginal itching and burning
Metronidazole (Flagyl) Oral, IV	Trichomoniasis, amebiasis		Is an amebicide and trichomonacidal agent		2 g given as single dose or 250 mg tid for 7 consecutive days; male partner should also be treated	Nausea, vomiting, anorexia, headache, diarrhea; rarely, seizures, peripheral neuropathy
Antiretroviral
Zidovudine (AZT, ZDV, Retrovir) Oral	Human immunodeficiency virus (HIV) infection	Blocks reverse transcriptase		200 mg po tid or 100 mg po 5 times a day; drug of choice to initiate treatment			Fatigue, headache, rash, nausea, seizures, severe bone marrow depression, confusion, agitation
Erectile Dysfunction Drugs
Sildenafil citrate (Viagra) Oral	Impotence	Aids in penile erection		25 mg, 50 mg, or 100 mg 1 hour before sexual activity; may interact with drugs containing nitrates such as nitroglycerin			Headache, diarrhea, flushing, dyspepsia, nasal congestion, hypertension, increased sensitivity to light, abnormal erection or ejaculation.
Vardenafil (Levitra) Oral	Impotence	Aids in penile erection		10 mg 1 hour before sexual activity Dose may increase to 20 mg or decrease to 5 mg based on efficacy and side effects			Headache, dizziness, hypotension, angina pectoris, dyspepsia, arthralgia, flushing, blurred vision, abnormal erection or priapisim (prolonged or painful ejaculation)

aTrade names given in parentheses are examples only. Check current drug references for a complete listing of available products.

bAverage adult doses are given. However, dosages are determined by a physician and vary with the purpose of the therapy and the particular patient. The doses presented in this text are for general information only.