One of the most interesting aspects of early development is the remodeling ofthe cell cycle from rapid cell divisions, apparently lacking G1 and G2 phases, to slower cell cycles with measurable G1 and G2 phases and checkpoints. During this remodeling, maternal mRNAs that specify cyclins are deadenylated, and zygotic genes are activated to produce cyclins. Audic et al. (2001. Mol. and Cell. Biol. 21: 1662–1671) suggest that dead-enylation requires transcription of zygotic genes. Present a diagram that captures the significant features of these findings.
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