two possible starting materials using a williamson ether synthesis method.Please explain
two possible starting materials using a williamson ether synthesis method.Please explain two possible starting materials using...
Calculate the theoretical yield in grams for the Williamson ether synthesis of phenacetin. (density of p-phenetidine is 1.065g/mL)Don't know if this helps but, the starting quantity of p-acetamidophenol is 1.51g
9. Show two pathways to synthesize cyclopentyl ethyl ether using the Williamson ether synthesis. Which one is preferred and why? (4 pts)
Williamson Ether Synthesis of Guaifenesin Starting Materials - 2-methoxyphenol (guaiacol): 550 uL - 3-chloro-1,2-propanediol: 500 uL - Sodium hydroxide: 1 mL of 6M Product - Guaifenesin What is the yield expected in (g) and (mmoles)?
The ether shown can be prepared using a Williamson ether synthesis; that is, by reacting an alkoxide ion with an alkyl halide. Draw the alkoxide ion and alkyl bromide that you would combine to make the ether with the highest possible yield. You may omit the metal cation counterion that accompanies the alkoxide ion for the purposes of this question. Include all lone pairs and nonzero formal charges. 1 stattomat
4) Briefly explain why the following molecule cannot be produced using Williamson ether synthesis. 4 pts Note: a complete answer will illustrate the two theoretical William ether synthetic pathways that could be used to synthesis the product (1 pt each) and explain why each pathway would not yield the desired product (1 pt each). Bonus: Provide a different synthetic pathway that produces the ether shown above. (I could do it in a single step!). (bonus 2 pts).
e) Typically. Williamson ether synthesis is conducted using Na, a very strong base in the reaction in d. however, the Williamson ether synthesis was accomplished with K.CO a much weaker base Why can K.CO, be used for this Williamson ether synthesis? n What general type of reaction is occurring here? g) Predict the reagents, then propose a mechanism (Hint: don't reduce the ester) OCH,
Outline two methods for preparing isopropyl methyl ether by a Williamson synthesis. One method gives a much better yield of the ether than the other, explain your answer.
Could the Williamson Ether synthesis be carried out using any type of alkyl halide? Why/why not. Draw the mechanism for the Williamson Ether reaction using bromoethane and t-butyl bromide and relate it to your answer.
How would you prepare benzyl methyl ether using a Williamson ether synthesis? The list of reagents to choose from are: 2-Chloro-norborane, Benzyl chloride, 2-Chloro-2-methylpropane, 4-Chloro-1-butanol, and Chlorobutane. I was reading online and it kept mentioning SN2 reactions, using an alcohol, and an alkyl halide for the synthesis. My guess would be using Benzyl Chloride and another one with an OH attached, but I could be completely wrong. Please help and explain by showing the reaction mechanism. Thank you so much!...