Question

Draw the major product formed in the following reaction of an epoxide with methoxide in methanol.

Draw the major product formed in the following reaction of an epoxide with acidic methanol.

Answer 1

Draw the major product formed in the following reaction of an epoxide with methoxide in methanol.

Answer 2

draw the major product formed when the following epoxide reacts with aqueous acid

Answer 3

Concepts and reason

The three-membered cyclic ring containing 2 carbon atoms and 1 oxygen atom is represented as an epoxide. Epoxides are also known as cyclic ethers. The opening of an epoxide follows an attack. An epoxide ring opening depends on the type of nucleophile present.

Fundamentals

In the presence of a weak nucleophile, the nucleophile attacks an epoxide on its more substituted site and follows a type reaction. An example for a weak nucleophile is.

Example:

In the presence of a strong nucleophile, the nucleophile attacks an epoxide on a less substituted site and follows a type reaction. An example for weak nucleophile is.

Example:

Ans: