![44) (3 pt) The following pedigree analyzes linkage between the ABO blood group and nail patella syndrome. Determine the Lod score for the data set (use the offspring in the 3rd generation) assuming a recombination frequency of 0.2. What does the asterisk mean? What information does the Lod score and your result suggest? Lod log. (-0 (0)o5)*] Note: the data available in the first generation provide information regarding assignment of recombinants and non-recombinants (the reason the equation is not split in halves). Ao 8o ■TO AB O0 AO AO AO BO AO BO AO BO Nail-patella syndrome = or Blood Types = 00, AB, BO, AO Answer_](http://img.homeworklib.com/questions/4c350ae0-7338-11ea-8afb-33d7468b7122.png?x-oss-process=image/resize,w_560)
Homework Answers
Lod score = log 10 [((1- theta )nr (theta)r / 0.5nr+r ]
recombination frequency is 0.2 , theta = 0.2
n is number of non recombinants = 8
r is number of recombinants =2
Putting the values in the formula , we get 0.4288
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44) (3 pt) The following pedigree analyzes linkage between the ABO blood group and nail patella...
Does this pedigree suggest any linkage between the gene that causes nail- patella syndrome and the...
Does this pedigree suggest any linkage between the
gene that causes nail- patella syndrome and the gene that causes
blood type?
Please explain fully to include phenotype, genotype,
type of inheritance, and anything else that well assist in the
understanding of this pedigree.
I get that the IBi gene is linked blood type to
nail-patella disorder, but how do I understand that from the
material presented.
Thank you for assistance in understanding this
material.
In humans, a rare dominant disorder...
The autosomal dominant disease nail-patella syndrome is linked to the ABO blood type locus. The pedigree...
The autosomal dominant disease nail-patella syndrome is linked to the ABO blood type locus. The pedigree below shows a family in which some individuals are affected by nail-patella syndrome. The blood type of each individual is given as capital letters above each individual symbol. The image can also be downloaded here: Figure B Final.pdf A B - 2 AB II 2 A B B B A B B A 2 3 4 5 6 7 8 Can you explain this...
The autosomal dominant disease nail-patella syndrome is linked to the ABO blood type locus. The pedigree...
The autosomal dominant disease
nail-patella syndrome is linked to the ABO blood type locus. The
pedigree below shows a family in which some individuals are
affected by nail-patella syndrome. The blood type of each
individual is given as capital letters above each individual
symbol.
Can you explain this pattern without a cross-over event? If not
in which individual did the cross-over occur?
А. B — 1 2 АВ 0 ІІ 1 2 A B B B A B B A...
Does this pedigree suggest any linkage between the
gene that causes nail- patella syndrome and the gene that causes
blood type?
Please explain fully to include phenotype, genotype,
type of inheritance, and anything else that well assist in the
understanding of this pedigree.
I get that the IBi gene is linked blood type to
nail-patella disorder, but how do I understand that from the
material presented.
Thank you for assistance in understanding this
material.
In humans, a rare dominant disorder...
The autosomal dominant disease nail-patella syndrome is linked to the ABO blood type locus. The pedigree below shows a family in which some individuals are affected by nail-patella syndrome. The blood type of each individual is given as capital letters above each individual symbol. The image can also be downloaded here: Figure B Final.pdf A B - 2 AB II 2 A B B B A B B A 2 3 4 5 6 7 8 Can you explain this...
The autosomal dominant disease
nail-patella syndrome is linked to the ABO blood type locus. The
pedigree below shows a family in which some individuals are
affected by nail-patella syndrome. The blood type of each
individual is given as capital letters above each individual
symbol.
Can you explain this pattern without a cross-over event? If not
in which individual did the cross-over occur?
А. B — 1 2 АВ 0 ІІ 1 2 A B B B A B B A...
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