Does this pedigree suggest any linkage between the gene that causes nail- patella syndrome and the gene that causes blood type?
Please explain fully to include phenotype, genotype, type of inheritance, and anything else that well assist in the understanding of this pedigree.
I get that the IBi gene is linked blood type to nail-patella disorder, but how do I understand that from the material presented.
Thank you for assistance in understanding this material.
Yes there is strong linkage between genes for nail patella syndrome and those for blood groups ABO due to being located on same loci of 9th chromosome . There is no crossing over between two genes . Where ever dominant blood group alleles are present in pedigree chart like A, B we se trait of diseaes is there . Trait is autosomal dominant where presence of only single allele sufficient to bring the effect .
Does this pedigree suggest any linkage between the gene that causes nail- patella syndrome and the...
Nail patella syndrome is a rare autosomal dominant condition causing misshapen nails and kneecaps. The Nail patella gene is approximately 12 map units apart from the I gene which determines ABO blood type.Nail patella syndrome (N) is dominant to normalIA is codominant to IB; IA is dominant to iIB is codominant to IA ; IB is dominant to iIA IA and IA i = Type A bloodIB IB and IBi = Type B bloodIA IB = Type AB bloodii = Type...
44) (3 pt) The following pedigree analyzes linkage between the ABO blood group and nail patella syndrome. Determine the Lod score for the data set (use the offspring in the 3rd generation) assuming a recombination frequency of 0.2. What does the asterisk mean? What information does the Lod score and your result suggest? Lod log. (-0 (0)o5)*] Note: the data available in the first generation provide information regarding assignment of recombinants and non-recombinants (the reason the equation is not split...
08 - Lola For the pedigree shown here, nail-patella syndrome was found to be linked to which blood type? ОА O AB None of these OB
The autosomal dominant disease nail-patella syndrome is linked to the ABO blood type locus. The pedigree below shows a family in which some individuals are affected by nail-patella syndrome. The blood type of each individual is given as capital letters above each individual symbol. Can you explain this pattern without a cross-over event? If not in which individual did the cross-over occur? А. B — 1 2 АВ 0 ІІ 1 2 A B B B A B B A...
thats all the information that was given. Nail patella syndrome is a rare autosomal dominant condition causing misshapen nails and kneecaps. The Nail patella gene is approximately 12 map units apart from the l gene which determines ABO blood type. Nail patella syndrome (N) is dominant to normal • IA is codominant to 1B: 1A is dominant to i • B is codominant to 1A, B is dominant to i • A 1A and IA i = Type A blood...
The autosomal dominant disease nail-patella syndrome is linked to the ABO blood type locus. The pedigree below shows a family in which some individuals are affected by nail-patella syndrome. The blood type of each individual is given as capital letters above each individual symbol. The image can also be downloaded here: Figure B Final.pdf A B - 2 AB II 2 A B B B A B B A 2 3 4 5 6 7 8 Can you explain this...