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A 30-year-old woman is seen by her physician during her first pregnancy. Her diet for the last year or two consisted of 4 two
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Red blood cells(RBC) indices are the blood test used to the quantity and physical characteristics of different type of cell that was found in blood and it also called as Complete blood count. Red blood cells contain hemoglobin and play a vital role which carries oxygen and nutrients throughout the body.

It can be divided into three parts:

  • Mean Corpuscular Volume (MCV),which is used to measure the red blood cell size.
  • Mean Corpuscular Hemoglobin (MCH),which is used to measure the amount of hemoglobin that is present per red blood cell.
  • Mean Corpuscular hemoglobin concentration(MCHC),which is used to measure the amount of hemoglobin and size of red blood cell.

Given values for calculating RBC indices:

  • Hematocrit(Hct): 18%
  • RBC count:1.5\times 10^{^{6 }}\textsc{}/micro liter
  • Hemoglobin(Hb): 6.0g/dl

According to the American Association of clinical chemistry normal range:

  • MCV:80-96 femtoliters
  • MCH:27-33pico grams per cell
  • MCHC: 33.4-35.5 g/dl

Mean Corpuscular Volume(MCV):

                               = Hematocrit(%) /RBC multiplied with 10

                                 18/1.5\times 10^{^{^{^{6}}}}\times 10

                                 120 femtoliter

Mean corpusucular hemoglobin(MCH):

                                 Hemoglobin(g/dl)/RBC multiply with 10

                                  6/1.5\times 10^{6}\times 10

                                 40 pg/cell

Mean corpuscular hemoglobin concentration(MCHC)

                                Hemoglobin(g/dl) / Hematocrit(%) multiply with 100

                                  6/18\times 100

                                  33.3 g/dl

2.Based on the above investigation data:

Mean corpuscular volume is more compare to normal indicate that patient red blood cell is larger than normal.This is called Macrocytic anemia.

Causes for High MCV:

  • Deficiency of vitamin B12
  • Chemotherapy
  • Preleukemia

Mean corpuscular hemoglobin is high compare to normal indicates that hemoglobin concentration per red blood cell is high.

Causes for high MCH:

  • Spherocytosis
  • Sickle cell anemia
  • Homozygous hemoglobin C disease
  • Blood infection
  • Tumor

           

                              

                              

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