3. Provide a complete curved-arrow mechanism for each of the following transformations OH 에 HAOLO 1....
4. Provide a complete curved-arrow mechanism for each of the following transformations involving conjugate addition Note that no stereochemistry is shown or implied in any of these reactions, and you may neglect it in your mechanisms as well. a. For this mechanism, you may assume that the reagent NaBH.CN behaves just like NaBHs, and that it preferentially performs 1,4-addition to unsaturated carbonyl compounds. O ! OME OMe H 1. NaOE, ETOH 2. NaBH CN, MOH oMe ОMe OME OME EtOXOE...
15. Provide a curved arrow mechanism for each of the following transformations. OH (a) CH3ONa CH3OH HBO Br (b)
15. Provide a curved arrow mechanism for each of the following transformations. OH (a) fyr CH3ONS CH3OH as HBr Br (b)
2. Provide a complete curved-arrow mechanism for each of the following transformations ed on 2 KO'Bu BUOH Etoo (1 equiv)
Provide a curved arrow mechanism for the reaction OH NaOH (aq) OH
Chemistry 12A Substitution and Elimination Reactions 1. Provide complete curved-arrow mechanisms for the following transformations, Label the overall mechanism as: E1, E2, S,2, or Sy1 and explain in 1 sentence WHY that mechanism is favored. Br OH OH Br кови Hао Br "ОН conc. H2SO4 "Он
Problem 3. Draw a full mechanism with arrow-pushing accounting for the following transformations: a) NaOCH3 noolhyn ne ů OCH3 OCH3 Haco н,CO CH3OH for Ő OCH b) (Hint: think retro-aldol first) NaOH OH EtOH
Predict the product and provide a stepwise curved arrow mechanism for the following reaction. OH OH H2SO4 heat
7. Provide a complete, arrow-pushing mechanism for each of the reactions below.(7 pts. each) NaOH (aq) then heat (a) HO NaOH ini EtOH/H20 (b)
Using the curved-arrow formalism, provide a mechanism that accounts for the following transformation. (5 pts) 1. OH НА OH 2. Using the curved-arrow formalism, provide a mechanism that accounts for the following transformation. (10 pts) H3O но C) OH