5. Diazotization gives diazonium salt which then loose N2 to form elimination product and Substitution product.
Wolff kishnner Reduction( N2H4/KOH) convert ketone into alkane.
DiBALH convert the ester(lactone) into aldehyde and alcohol.
Nucleophilic addition of HCN gives caynohydrin.
5. Show how the following reaction would proceed. NH2 1.) NaNO2, HCI 2.) H2O Nucleophilic Substitution...
ТД на, . 4. Show the mechanism of the following two eliminations. What is each elimination scheme named? *ΝΗ A H2O2, heat 1:07. heat 1.) CH31 (excess) 2.) Ag,0,H,O 5. Show how the following reaction would proceed. NH2 1.) NaNO2, HCI 2.) HO Nucleophilic Substitution Product Elimination Product
2. (2 points) Draw the reaction mechanism for the following reaction: NH2 -N 1. NaNO2, HCI, H20 2. NaOH, OH -OH then H3O+
Predict the major product of the following reaction. NH2 1. NaNO2, HCI 2. CuCN NH2 CN NH2 CH_NH2 CN NC IV II -
lect the correct product for the following reaction. [3) ?? NH2 1) NaNO2 HCI, 0°C 2) EtOH, H HO NH2 Eto NH2 NH2 HO OEt HO OEt OEt
Write the products of these reactions -NH2 1. NaNO2, HCI 2. CuCN 1. N(CH3)3 2. Ag20, H20 3.A 1. LAIHA 2. H20 NaN3 1. LATHA 2. H2O NaCN 1. LIAH 2. H20 Br NaCN H. Ni HNO3 H2SO4 NaOH H20 1. NaNO2 HCI 2. HBF 4 CH3 HNO3 Na Cr207 H2SO4 H2SO4 Sn HCI 1. NaNO2 HCI 2. CuCN
Part 2. Nucleophilic substitution The reaction below is a nucleophilic substitution. Answer the following questions OH NaOH MeOH Br 1. What is the intermediate? (4 pts) 2. What is the product? Pay attention to stereochemistry where appropriate. (4 pts) Part 3. Integrated question The reaction below has been asked in our lecture. What are reagents required to complete the synthesis? (Hints: two steps) (6 pts) SCH3
What is the major product in the following reaction? LiAIHA N ? H2O O Quid O NH2 O NH2 O OH What is the major product in the following reaction? 1. CH31 (excess) ? NH2 2. Ag20, H20, heat HN a Which starting material would most easily be converted to the amide below through nucleophilic acyl substitution? NH2 o H O oll OH What are the best reagents for the following transformation? NH2 NH O2N 1. H2SO4, HNO3 2. CH3COCI,...
E) V 57. Identify the best product for the reaction. NH2 1. NaNO2, HCI, O C 2. CuCN A) CHANH B) NH₂ CEN D) CH= H
1. (Ph),c-OH + HCI (Ph) C-Cl + H2O 2. M OH + NaH - ^ nö Nu + H₂ a = Proton transfer b = Lewis acid base c = Radical chain substitution d = Radical chain addition e = Electrophilic addition f=E1 Elimination g=E2 Elimination h = Sn1 Nucleophilic substitution i = SN2 Nucleophilic substitution Identify the mechanism by which each of the reactions above proceeds from among the mechanisms listed. Use the letters a - i for your...
Which of following is the best starting material for the reaction below? 1. (CH3)2NH ? 2. LIAIHA 3. H20 'N NK CN NH2 What is the major product in the following reaction? 1. DIBAL 2. H20 O H O OH OH СІ Which reaction sequence would accomplish this transformation? CN H2SO4/HNO3 Br2 NaNO2/HCI CuCN O Br2/FeBr3 H2SO4/HNO3 KF NaNO2/HCI O H2SO4/HNO3 Zn(Hg)/HCI NaNO2/HCI CuCN o H2SO4/HNO3 Zn(Hg/HCI NaNO2/HCI HBF4