Are the highlighted protons(Ha and Hb) homotopic, enantiotopic or diastereotopic? Ph Ls JHO Ho

Question

Question

Are the highlighted protons(Ha and Hb) homotopic, enantiotopic or diastereotopic?

Answer 1

Answer #1

1st molecule, Ha and Hb are related by C2 axis of symmetry. Thus they are enantiotopic in nature.

2nd and 3rd molecules have diastereotopic hydrogen atoms as they are neither related by plane of symmetry nor by C2 axis.

Answer 2

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