Question

1. State the structural relationship between the highlighted protons (homotopic, enantiotopic, diastereotopic). Recall that there are two ways to solve these problems that we covered in class: the replacement test or symmetry analysis. See section 15.4 in Klein q ue lle

Answer 1

The topicity of the highlighted protons in the given compunds are given in the following pictures,

"Highlighted protons are" will ll Diastereotopic H Enantiotopic. AL H H 3. I 11111 Homotopic Enantiotopic OH H 4 Homotopic Emantis topic nun

port . ( Homotopic H Main 1 Enantiotopic.