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The physician orders 20 mg of fludarabine phosphate IV for the patient with leukemia. The nurse...

The physician orders 20 mg of fludarabine phosphate IV for the patient with leukemia. The nurse has a 50 mg vial for reconstitution. The package insert gives the instructions for reconstitution: When reconstituted with 2 mL of Sterile Water for Injection, each mL of the resulting solution will contain 25 mg of fludarabine phosphate, 25 mg of mannitol, and sodium hydroxide to adjust the pH to 7.7. After reconstitution, how many mL will the nurse administer to the patient via the IV route? _______

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Answer #1

Answer:- 0.8 ml
Explanation:-
- ordered dose = 20 mg of fludarabine phosphate IV
- on hand = 2 mL of Sterile Water(25*2 mg of fludarabine phosphate, 25*2 mg of mannitol)
                                
=> Infusion rate = 50 mg is present in 2 ml
      Then 20 mg will be equal to =>
                 =(2/50)×20
                = 0.8 ml

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