Question

Model 8: Selectivity of the Photo-Halogenation Reaction Radical halogenation with Fis i olent and dangerous limiting the usefulness of this reaction in organic synthesis Radical halogenation with lis so slow as to be useless in organic synthesis Radical halogenation with Br, is just right! It is very useful in organic synthesis. The rate is manageable and reactions with Bry are very selective. (A selective reaction gives close to 100% of a single product. An unselective reaction gives a mixture of products.) Table 8: Relative Preference of Halogens for 1,2,3,Ally & Benzyl Sites Halogen (X) | X sub, for X sub, for X sub. for a X sub. for a X sub. for a H H in a l a H in a 2" Hina 3* H in ally! in benzyl Position Position Position Position Position Fluorine (F) 1 1.2 1.4 1.5 1.6 Chlorine (Cl) 1 10 Bromine (Br) 1 100 2000 10.000 100.000 For Example: сн. - CH₂ CH₂ F CH CH, HAC Rxn VI da 92 -CI 1 CH₂ CH₂ Rxn VII CHCI: CH₂ H₃C/ 5 product ratio CHE CHE Brd Rxn VIII Hoc CH, H₃ C CH₃ H₃C 2000 produce 2 Critical Thinking Questions 14. Fluorination and Chlorination are less selective than Bromination. Do the product ratios for Rxn VI-VII support this statement? Explain. BE: 15. Explain how the ratio 1.4 to 9 was arrived at in Rxn VI in Model 8. 16. Is your explanation consistent with the 2000:9 ratio in Rxn VIII?!

questions 14,15,and16 please

Answer 1

♡ In reactions given in case of Bra preferenu for 304 = 2000 chlaerment probing No. of -4 = 1 dy te conly tease) same initiof rosette is used in both ty hey hydrogen ( 7°, 10) one placement passry my le compared if we only talk about the 324 geplant soome insting subroty de Conly 1, 3 - 4 in each tako for 3% seplemt code to any of F = 1.4 = Creast selective for 30-4) C = = Br = four (most replacements 30 selecting tot = 2000x1 forefrence for 1-4 = 1 Nowy 1-4 = 9 1. selecharity total = 9x1=9 g ovo is je consistent ryho = 1 30 4 Number of for 1.489 for F selecting for 30 = 1.9 i o selecting toff = 1.4x1=104 selecting for 10 = 1 tot Nocy 104 = 9 le 1 selechy toth = gxleg