Question

Psychoactive drugs usually exert their subjective and behavioral effects by modifying synaptic transmission in one or more of the following ways: (1) increasing or decreasing transmitter synthesis, (2) reducing transmitter inactivation by inhibiting enzymatic breakdown or blocking reuptake, (3) stimulating transmitter release, and (4) acting as agonists or antagonists at transmitter receptors on the postsynaptic or presynaptic (i.e., autoreceptors) cell.

What are 3 targets for psychoactive drugs, including complementary agonist and antagonist drug actions?

1 Drug serves as NT precursor Precursor 2 Drug inhibits NT synthesis Enzyme 8 Drug stimulates autoreceptors; inhibits release of NT 3 Drug prevents storage of NT in vesicles Neurotransmitter 9 Drug blocks autoreceptors; increases release of NT 4 Drug stimulates release of NT 5 Drug inhibits release of NT Molecules of drugs 10 Drug inhibits NT degradation 6 Drug stimulates postsynaptic receptors 11 Drug blocks reuptake 7 Drug blocks postsynaptic receptors Postsynaptic receptor Degrading enzyme Postsynaptic cell Figure 3.14 Summary of the mechanisms by which drugs can alter synaptic transmission NT = neurotransmitter; + denotes a mechanism that stimulates or facili- tates transmission; - denotes a process that inhibits transmission.

Answer 1

Psychoactive drugs have anatomical action in the CNS. example: Mood stabilizers, Hypnotics, antipsychotics and anxiolytics, antiepileptics and antidepressants. It changes the state of consciousness. It acts as how neurotransmitters work in the synapse of CNS. there are 3 targets that psychotic drugs make includes blocking the reuptake of drugs synapse of CNS, it changes the conscious state and increases the production of the neurotransmitter acetylcholine, chemical components of drugs mimic the neurotransmitter action.
There also agonists that mimic the function of neurotransmitters and antagonists block the action of neurotransmitters and reuptake neurotransmitters at the synapse. agonist and antagonist bind the receptor, functional group of drug complementary with the surface on the receptor.