Question

Please write 1 paragraph for each of the following (total 3 paragraphs) and each paragraph shall be no more than 9 sentences.

1. Please discuss ONE SPECIFIC antidiabetic medication Give class; actions and uses; side effects & adverse reactions; contraindications & toxicity; administration; any other pertinent information.
2. Please discuss ONE SPECIFIC medication for urinary disorder. Give class; actions and uses; side effects & adverse reactions; contraindications & toxicity; administration; any other pertinent information.
3. Please discuss ONE SPECIFIC medication for Sexually Transmitted Disease. Give class; actions and uses; side effects & adverse reactions; contraindications & toxicity; administration; any other pertinent information.

Answer 1

One specilic anthdiabehe meolitation is Biguanides 4etm Metformin class Activates the enyme AMP dependont protrin kinau Mechanis m of achen his results in decreased hepate glutone ogenests utili2aton of glutose in Inireasd peripheral skele tal mUscle and tad 7his leads to intease in 9ycogen storage n tho ske le tel mustle, tnoeased fa ty ad oxidatan and decoeased 1pogenesis Inhibition of alimentary absorphn ob glutose Uses Used in patonts with type -2 DM etther alone or combinaton antidiabetic agents with other sde oflect Anorexio, nausea, vomithng, diahoea, toss o welght Skin ashes Prolonged uses cause vitamin n delicieny Contraindicaton- e Contraindicated in pat ents with a cora hnine eleaahie moderate SP vPre heart failuve, atote less than 60mLImin myocardial arcton and tho Se undergoihg majos surgey Toxici Pregressive enal bailure eventualliy leads to metfosmin actumulahon and toxicily Al ministraton At 1st 500 mg2 imes adaiy tken wi th the morning and ovening mals or 65omg a dey thken with the morning meal aly

one sperfic drug for urinay disorder is ohimora2ole sulphame thox azole + class-su lphona mide Acton-1+ produres spuenthal blockage ie tue druss intejer e twith turo SU methopaim Cuccessive steps n same me tabolic pathwey Para-aminobenzoic acid (PABA Folate syntha ta se Sulphamethoxa20le Dikydrofeicacid Dihydrofolate reductase Tinethopaim Tehahydrofolic adid UsesUsec! Urnary ract inechon caused -coli,Preteus at nterobatte Also usd in treatment of bacteal pro statitis Sideellat skin rashes gastrointestnal disturbane, exjoliative dermatibis eythema mu lhjorme Stevens Johh son syndome Contrainditabon- In patents with a known hyper sensitvity to timethoprim o sultonamides and in patipnts with documated megaloblashc anemia due to folate deliceny Aslo Also in prgnant teom because sultonamides pass the plaipnta may cause kernicteros Patient at and ave excreted in milk and Adminis traan oraly with water usualy taken 2 tmes a day

One speciic drug to Cexua ly Tasmitted Disease class-Tetrauyeine Acthon-Bind eversibly to 30s ibosomalskunit and thus prevent binding Is Donyeyc line amino ayl tRNA to mRNA ibosome 1omplex eand prevent the addition ol amino aci d to the gowing peptide chain Hence nhibit lbacterial protein synthesis Ricketteial nfectons, mycoplas ma pneumoniae, Chlamydhal iections eholera, Grute llos is, Plague, Anthrax leptos pi rosis, Gmedisease 4anuloma inguinalo, Acne Uses / 6de ellect Photo toxic iky Hepatotoxi city, Superinyecthion, discoloraton of Hecth due to deposiben of thelate in the tee th Hyper sensitiviyfacto (ontraindicated in Pregnant, Liver diseaso, Renal disease Lontraindirate Liver and khdney toxicity 7oxicits Administra hen Oral 200 y n1s day 6ollowe d ly maintonante dose my be as a sing le dose OT as 5o ma eve Lhours