Question

1) What generation of biomaterial would you categorize steel urgical staples as and why? 2) If researchers genetically modified silk worms to produce a different version of silk sutures that could be absorbed by the body, what generation of biomaterial would you categorize these sutures as and why? 3) You have three potential materials to choose from for designing a bone fixation plate. You run a series of tests and measure the following relative material properties: Material X -good biocompatability, great mechanical properties, very expensive Material Y - poor biecompatability, good mechanical properties, cheap Material Z- great biocompatability, acceptable mechanical properties, somewhat expensive Which material should you select and why?

Answer 1

Answer :

1) steel surgical staples coming under first generation biomaterials .

When synthetic material were first used in biomedical applications the using requirements were a suitable physical properties to match those of the replaced tissue with minimal toxic response of host.

So biologically inert or nearly inert material were used in order to reduce the corrosion and the releasing ions and particles after implantation to minimise immune response foreign body reaction .

2) silkworms are the current biological source of silk sutures but spider silk fiber have superior mechanical properties that are ideal for procedures requiring finer sutures such as ocular ,neurological and cosmetic surgeries .

3) material z _ great biocompatibility , acceptable mechanical properties and some what expensive .

Biocompatibility is related to behaviour of biomaterial in various context .

It refers to the ability of a material to perform with an appropriate host response in a specific situation .

So ,We should very much careful when designing fixation plate whether it is having great biocompatibility or not .

Material should have acceptable mechanical properties and material should not much expensive

We should see the affordability of maximum number of patients .