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A 20 yr old male with a family history of Type I Diabetes was seen by his physician due to incessant thirst (polydipsia) and

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a) Diabetic ketoacidosis, Renal failure, metabolic acidosis is the most likely diagnosis for this patient.

b) Hyperglycemia, Elevated urea and creatinine levels show the presence of ketones in the blood. High anion gap, decreased acidosis, decreased acid excretion, decreased bicarbonate reabsorption results in renal failure. The kidney fails to work results in the accumulation of sulfates, phosphates, urate.

c) Anion Gap = Sodium - (Chloride + Bicarbonate)

Sodium = 141

chloride = 102

Bicarbonate = 17

Anion Gap = 141 - (102 + 17)

Anion Gap = 22.0 mEq/L

The anion gap is increased in this patient due to the increased level of acidity in the blood as a result of disturbed metabolic processes.

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