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What is one major disadvantage of using a Lineweaver-Burk plot for determination of kinetic parameters from...

What is one major disadvantage of using a Lineweaver-Burk plot for determination of kinetic parameters from real data?

A.) A Lineweaver-Burk plot biases data with fast initial velocities

B.) The Lineweaver-Burk plots tend to be reliant on how reproducible the initial rate is

C.) The Lineweaver-Burk plot biases low concentration data

D.) all of the above

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