2. N-bromosuccinimide is a synthetically diverse reagent. List four additional types of reactions, other than oxidation...
2. N-bromosuccinimide is a synthetically diverse reagent. List four additional types of reactions, other than oxidation of a pyridines, in which NBS can be used. 3. Dihydropyrimidines can form with similar conditions and building blocks to the mechanism for the Hantzsch Ester following a Biginelli synthesis. Provide a mechanism for the formation of the following dihydropyrimidine. 4. Rosiglitazone, 12, is a type-2 diabetes drug that helps control the metabolism of carbohydrates and fatty acids. Provide a mechanism for the conversion...
4. Rosiglitazone, 12, is a type 2 diabetes drug that helps control the metabolism of carbohydrates and fatty acids. Provide a mechanism for the conversion of 7 to the pyridine 11. POCIE OH 150°C CHO Nah, DMF 80'C Mg, MeOH HOAC toluene, reflux